Taking high doses of gabapentin or taking it in a way other than as intended can increase the risk for a potentially life-threatening overdose. The tablets may be crushed and then snorted, or chewed up and swallowed, for a faster induction of the euphoric effects. When abused, gabapentin is typically taken in higher doses than would be prescribed. It may also be abused recreationally by people looking for a relaxing high, especially by those who abuse other drugs and/or alcohol. In particular, gabapentin may reduce anxiety and help with relaxation during withdrawal from these substances. ![]() Gabapentin may be particularly desirable to those who are dependent on alcohol, cocaine, or opioids, as it may help to smooth out withdrawal symptoms of these drugs in between doses. Outside of its intended use, and by those wishing to mitigate withdrawal from other substances of abuse, per the journal Practical Pain Management. NIDA further publishes that prescription and over-the-counter drugs are the most regularly abused drugs (after marijuana) by people aged 14 and older in the United States. The National Institute on Drug Abuse (NIDA) reports that more than 7 percent of Americans aged 12 and older had abused a psychotherapeutic drug in 2015. It may also cause “zombie-like” effects when abused. Gabapentin may be on the rise as a drug of abuse, as the Drug and Poison Information Centre (DPIC) publishes multiple reports of this drug being used to create a marijuana-like “high,” to induce euphoria and sociability, and to promote relaxation as it is being used outside of the bounds of a legitimate and necessary prescription. It is unclear exactly how gabapentin works in the brain and body. ![]() Gabapentin is an analogue of the naturally occurring brain chemical GABA (gamma-aminobutyric acid), which works as a tranquilizer, quelling anxiety and reducing brain seizures. Mayo Clinic reports that brand names for gabapentin within the United States include Neurontin, FusePaq, Fanatrex, Gralise, and Gabarone. It is also used as an adjunct medication to help with epileptic seizures. Gabapentin is a prescription medication used to help treat postherpetic neuralgia, a pain that people may develop after shingles.
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